Glycine Propionyl-L-Carnitine (GPLC): Mgbakwunye Kachasị mma Maka Nrụpụta Ahụ

Gịnị Bụ Glycine Propionyl-L-Carnitine (GPLC)

Glycine Propionyl-L-Carnitine na-ekwu okwu na-ezo aka n'ụdị njikọ njikọta nke propionyl-L-carnitine na amino acid glycine. Ekesa ya na ezi n’ulo dika Carnitine ma dikwa nkiti na nmebe Creine. Glycine Propionyl-L-Carnitine (GPLC) na-arụ ọrụ dị ka antioxidant, ọ na-ebutekwa ọgụ dị egwu megide nnwere onwe nnwere onwe yana ichebe na peroxidation lipid.

Ọzọkwa, ọ na-enyere aka n'ịmepụta ume site na-enyere aka na-ebufe fatty acids na-ebu ogologo n'ime mitochondria. Ọ na - enyere aka n'iwepụ ihe mkpofu - enyemaka carnitine na nchekwa nke ahụ site na ọrịa obi na ọrịa shuga. A na-ewere GPLC ka ọ nwee ọrụ nke na-akpali akpali ahụ ike ma na-eme ka mmega ahụ dịkwuo elu. Enwere ike iwere mgbakwunye ahụ yana mgbakwunye ndị ọzọ, dịka ọmụmaatụ, propionyl-l-carnitine l-arginine na niacin, nke na-enyere aka iji melite nrụrụ erectile (ED) n'ime ụmụ nwoke. Otú ọ dị, nweta ọgwụ ziri ezi site na dọkịta gị iji zere ị overụbiga mmanya ókè, nke nwere ike ịkpata nnukwu mmetụta dị egwu.

Propionyl-l-carnitine ụdị gụnyere; 3-propanoyloxy-4- (trimethylazaniumyl) butanoate, Glycine Propionyl-L-Carnitine (423152-20-9), L-carnitine propionyl, PLC, LPC, na Glycine propionyl-L-Carnitine Hydrochloride. Na Mgbakwunye nri na-ere n'okpuru aha ika dị iche iche dabere na ọnọdụ gị. Agbanyeghị, nke ahụ ekwesịghị ịbụrụ gị nsogbu; mediki ga enwe ike iduzi n’zuta ya.

Mgbakwunye a dị na ụlọ ahịa dị n'ịntanetị dị iche iche ebe ị nwekwara ike ibubata ya n'enweghị nsogbu. Dịka ọmụmaatụ, propionyl-l-carnitine Walmart na-anapụta n'ime obere oge enwere ike. Ọ baghị uru ebe ị nọ, jiri ekwentị gị ma ọ bụ kọmpụta gị mee iwu Walmart propionyl-l-carnitine. Ọ bụ ihe amamihe dị na ịme nyocha gị maka ndị na-ere glycine propionyl dịnụ tupu ịme mkpebi ikpeazụ gị. Gụọ nyocha propionyl-l-carnitine Reddit iji nweta nkọwa nke otu ndị na-ere ma ọ bụ mgbakwunye na-arụ ọrụ. Ndị ahịa na-ekwupụta n'eziokwu n'eziokwu ha gbasara mgbakwunye, nke nwere ike inyere gị aka ịhọrọ onye na-ere ahịa kacha mma. Dọkịta gị ga-abụkwa onye kachasị mma iduzi gị ebe na otu esi enweta mgbakwunye dị mma nke ga - enyere gị aka iru ihe mgbaru ọsọ gị.

Glycine Propionyl-L-Carnitine na L-Carnitine

A maara GPCL dị ka Carnitine's propionyl ester nke nwere ihe ọzọ nke glycine. N'ihi anụ ahụ nke enzymes esterase, Glycine Propionyl-L-Carnitine testosterone kwesịrị ịrụ ọrụ nke prodrug ma rụpụta glycine, Carnitine, yana propionic acid dị na ahụ mmadụ. Glycine Propionyl-L-Carnitine na L-Carnitine dị iche na otu akụkụ. Ha abuo na enyere aka na imeputa ike yana ahụ ike. Glycine propionyl-L-carnitine na-enyocha na-enyere ahụ gị aka ịgbake n'ọrịa ndị dị ka ọrịa obi.

Kama nke ahụ, a na-ejikarị L-Carnitine eme ihe n'ịgwọ mgbu nke ụkwụ yana ọrịa obi. L-Carnitine bụ kemịkalụ ebe Glycine Propionyl-L-Carnitine (423152-20-9) na-enyocha bụ molekụla. Na nkenke, testosterone Glycine Propionyl-L-Carnitine na-alụ ọgụ ka ọrịa L-Carnitine na-agwọ ọrịa.

Mmetụta Glycine Propionyl-L-Carnitine

Ndị na-esonụ bụ Nke a bụ glycine propionyl L uru carnitine:

• Inye ike. Propionyl-L-carnitine na-enyere ahụ aka imepụta ike. Ọ dị mkpa maka ịrụ ọrụ obi kwesịrị ekwesị, mmegharị nke akwara, n'etiti usoro ahụ ndị ọzọ. Ọ bụkwa ya na-eme ka ọbara na-ekesa n’ime ahụ.

• Na-emeso ọkwa testosterone dị ala. Ka nká nwere ike ime ka mmadụ nwee testosterone dị ala. Propionyl-L-carnitine tinyere acetyl-L-carnitine ruo ọnwa isii bụ ọgwụgwọ maka ala arụ ọrụ mmekọahụ, obi nkoropụ na ike ọgwụgwụ nke ụmụ nwoke. Nchikota a na aru oru dika testosterone synthetic.

• Angina ma ọ bụ obi mgbu. Iburu propionyl-L-carnitine site na ọnụ na-enyere ndị nwere angina ije ije ihu. Somefọdụ ndị mmadụ, o nwere ike belata ugboro ole nke mgbu obi.

• Ọ na-agwọ ọrịa obi mgbu na-adịghị ala ala. Mgbe ị banye na ọgwụ propionyl-L-carnitine na akwara, ọ na - enyere aka ịmịpụta mkpụrụ obi ka ọ dị mma n'ebe ndị mmadụ nwere ọrịa obi.

• Congestive obi nkụchi (CHF). Propionyl-L-carnitine bụ prodrug nke na-arụ ọrụ maka ndị nwere oke CHF na-agbanwe agbanwe. Ọ na - eme ka obi ha na - arụ ọrụ ma nyere ha aka ije ije ogologo ije.

• Glycine propionyl l carnitine na dysfunction erectile. Site na ịba ụba homonụ nke testosterone n’ime ahụ gị, mgbakwunye a na-edozi nsogbu nsogbu etrectile na-abawanye na ịbawanye na nwoke na nwoke.

• A na-agwakọta Propionyl-L-carnitine na Viagra (sildenafil) maka nsonaazụ kachasị mma na ụmụ nwoke nwere ED na ọrịa shuga. Ọzọkwa, ihe ndị akọwapụtara nwere protein propionyl-L-carnitine nwere ike ịkwalite arụmọrụ mmekọahụ.

• Ọrịa vaskụla nke Peripheral. Ọrịa Peripheral nwere ike ibute ọria veins ma ọ bụ ihe mgbu n'ụkwụ mgbe ị na-eje ije; ọnọdụ a na-akpọ ịkọwa ọnụ. Ọgwụ agịga ma ọ bụ ịmalite Propionyl-L-carnitine na-enyere ndị mmadụ aka na-enwe ihe mgbu ụkwụ ije ogologo ije.

• Ọrịa Peyronie (ọ na-eme ka anụ ahụ amụ)Otu ọgwụ a na-akpọ verapamil, yana propionyl-L-carnitine na-eme ka mmekọahụ nwee mmekọahụ, na-egbochi njọ nke ọnọdụ ahụ. Enwere ike iji mkpokọta ọnụ ma ọ bụ site na injections. Ọrịa Peyronie nwere ike ịchọ ịwa ahụ ma ọ bụrụ na ọ nweghị ya. N'ihi ya, Propionyl-L-Carnitine na-abịa napụta.

• Ọrịa afọ (ọnya afọ). Propionyl-L-carnitine bara uru iji belata ihe mgbaàmà na ndị ọrịa nwere ọnya afọ na-ejikwa ọgwụ ụfọdụ. Ọ nwere ike iwepụ ihe mgbaàmà ahụ.

 Nnyocha na Nsonaazụ Glycine Propionyl-L-Carnitine

• Ọrịa Crohn (ọrịa afọ)Nchoputa nke mbu gosiputara na iji propionyl-L-carnitine bu ihe na-ebelata ihe mgbaàmà nke ndi oria na oria Crohn.

• Ala ala ike ọgwụgwụ (CFS).Nnyocha na-atụ aro na propionyl-L-carnitine nwere ike melite ike ọgwụgwụ n'ozuzu maka ndị ọrịa CFS. N'ụzọ na-akpali mmasị, ọ bụrụ na agwakọta acetyl-L-carnitine na propionyl-L-carnitine, nsonaazụ ahụ adịghị arụ ọrụ karịa iji otu emeju ọzọ.

• Ike mmega ahụ. E gwuru ga-eme ka mmerụ ahụ dịkwuo elu, ike ịkwụsi ike mmega ahụ siri ike. Agbanyeghị, were nke ọma glycine propionyl-l-carnitine usoro onunu ogwu. Doagbaso mmezi a nwere ike ibute nsonaazụ HCl mmetụta nke glycine propionyl-l-carnitine, nke nwere ike ịdị ọnụ iji gbanwee.

Olee nri ndị bara ụba na Glycine Propionyl-L-Carnitine?

Glycine propionyl-l-carnitine ka ahutara na:

• Ala ahịhịa juru.
• beef
• Anụ ezi
• Chicken chiiz
• mkpụrụ

Etu ị ga-ewere Glycine Propionyl-L-Carnitine

A na-ere Propionyl-L-Carnitine dị ka mgbakwunye. Nwere ike ịchọta ya na ụlọ ahịa mpaghara gị ma ọ bụ ụlọ ahịa ọgwụ. Ndị na-eme egwuregwu nwere ike irite uru dị ukwuu site na ị itụ ya ebe ọ bụ na ọ na-enyere ahụ aka ịnọgide na-enwe ọrụ akwara dị mma ma na-eme ka ikike ikpo ọkụ nke mkpụrụ ndụ dịkwuo ike. Lee ndị a tụrụ aro Glycine Propionyl-L-Carnitine (423152-20-9) usoro onunu ogwu akwadoro site na nyocha sayensị.

 EGO:

• Iji gwọọ nsogbu arịa ọbara: Were 500-2000 mg propionyl-L-carnitine ugboro abụọ n'ụbọchị.
• Iji dozie CHF (ọrịa obi ụkọ), angina ma ọ bụ obi mgbu; Were 500 mg propionyl-L-carnitine ugboro atọ n'ụbọchị.
• Iji bulie testosterone na ụmụ nwoke mere agadi: Were gram abụọ nke propionyl-L-carnitine na gram abụọ nke acetyl-L-carnitine kwa ụbọchị.
• Glycine propionyl l carnitine na dysfunction erectile: Were gram 2 nke propionyl-L-carnitine kwa ụbọchị na 50 mg nke nyere ugboro abụọ kwa izu. Nchikota nkwekorita nke propionyl-L-carnitine l-arginine na niacin ga - ewulite mmeko nwoke na nwanyi. Agbanyeghị, usoro onunu ogwu kwesiri ibu 250mg fir propionyl-L-carnitine na 20mg maka niacin. N'aka nke ozo, ị nwekwara ike were mgbakwunye na arginine 2500 mg kwa ụbọchị.
• Maka ọrịa Peyronie: gram 2 nke propionyl-L-carnitine kwa ụbọchị yana injections nke ọgwụ a na-akpọ verapamil.
• Maka ọnya afọ: 0.5-1 gram nke propionyl-L-carnitine ugboro abụọ kwa ụbọchị.

I nwekwara ike ijikọ l -carnitine, na Cialis, mana nweta usoro ọgwụgwọ kwesịrị ekwesị site n'aka ndị ọkachamara ahụike maka ahụmịhe kachasị mma.

NSOGBU:

Maka ọrịa obi na nsogbu arịa ọbara: Ọkachamara ahụike na-eduzi inyonya propionyl-L-carnitine, usoro ana - akpọ IV.

Glycine Propionyl-L-Carnitine mmetụta na nchekwa

Propionyl-L-carnitine bụ ihe dị mma maka ọtụtụ mmadụ mgbe ọnụ ma ọ bụ tinye ya n ’akwara site n’aka dọkịta ọkachamara. Ọ nwere ike ibute afọ ọsịsa, afọ mgbu, afọ mgbu, vomiting, azụ mgbu, na obi ọrịa. Ọzọkwa, ọ nwere ike ibute iku ume, mmamịrị, ma ọ bụ ọsụsọ.

ịkpachara anya

Ndị ọrụ afọ ime na ndị na-enye nwa ara: A maghị ihe dị ukwuu maka ojiji nke propionyl-L-carnitine maka ịctụ nwa. Jiri nwayọ gaa n’ihu ma zere iji ya.

"Underactive thyroid" (hypothyroidism): propionyl-L-carnitine nwere ike ime ka hypothyroidism ka njọ ma ọ bụ ọgwụgwọ ọgwụgwọ thyroid adịghị arụ ọrụ. Chemical dị na ọgwụ ahụ, ya bụ, L-carnitine, na-egbochi hormone thyroid. Ọ kachasị mma iji zere propionyl-L-carnitine ma ọ bụrụ na ị nwere hypothyroidism.

Ọ ọdịdọ: mmadụ ole na ole nwere akụkọ ihe ọdịnala na-ekwu na mmụba nke ogo yana ọnya ọnya mgbe ha jisịrị L-carnitine. Enwere ohere dị ukwuu na nke a nwere ike ime na propionyl-L-carnitine ebe ọ nwere kemịkal yiri ya.

Mmekorita nke GPLC na ogwu ndi ozo

• Iji nọrọ n'akụkụ nchebe, gakwuru dọkịta gị tupu ịmalite na-ewere GPLC. Bụrụ na ị na-ewere Acenocoumarol (Sintrom), ị ga-etinyekwa dọkịta gị maka na ọ nwere ike inwe mkparịta ụka dị nro n'ihi na ọ nwere ike belata ịmịnye ọbara ebe GPLC nwere ike ịbawanye mmetụta Sintrom.

• Warfarin (Coumadin) bụ ọgwụ ọzọ ị nwere ike ịnakọta yana mgbakwunye glycine propionyl-l-carnitine. Otú ọ dị, jide n'aka na ị ga-enweta ezigbo usoro ọgwụgwọ site na ọgwụ gị. Usoro onunu ogwu nwere ike ịdị iche dabere na ọnọdụ dị n'okpuru ọgwụgwọ.

Ebe ị ga-azụta mgbakwunye Propionyl-L-Carnitine

Dịka ngwaahịa ọgwụ ọ bụla ọzọ, ị nwere ike ịzụta mgbakwunye glycine Propionyl-L-Carnitine sitere na nyiwe dị iche iche dị n'ịntanetị ma ọ bụ ọbụna na ụlọ ọgwụ ahụ ike. Agbanyeghị, ihe ịma aka na-abịa n'ịhọrọ ndị na-ere ahịa kwesịrị ekwesị nke ga-enye gị ngwaahịa dị mma. Enwere ọtụtụ ndị na-ere glycine Propionyl-l-Carnitine, ma nke anụ ahụ ma n'ịntanetị. Otú ọ dị, nke ahụ ekwesịghị ịtụ gị ụjọ, ihe ịchọrọ bụ iwepụta oge gị ma mee nyocha banyere ndị na-ere ahịa glycine Propionyl-l-Carnitine dị.

I nwere nnwere onwe ịzụta glycine Propionyl l-Carnitine nnukwu ntụ ntụ ma ọ bụ naanị ezuru gị iji. Cheta, iji nweta usoro ọgwụgwọ ziri ezi mgbe niile site n'aka onye ọrụ ahụike ka ị nwee ike ịnụ ụtọ glycine propionyl-L-carnitine kachasị. Tụlee ịgafe propionyl-l-carnitine Redditreviews iji nweta nnyocha nke ahụmịhe onye ọrụ dị iche iche. I nwekwara ike ịzụta l carnitine na Cialis site n'aka otu ndị na-ere ahịa, n'etiti mgbakwunye ndị ọzọ. Brandsdị Propionyl-l-carnitine dịgasị iche site n'otu ebe gaa na nke ọzọ, mana ọ ka bụ otu mgbakwunye ahụ. Kwenye dọkịta gị tupu ị nye iwu ahụ.

Nkeji edemede site:

Dọkịta Liang

Co-guzobere, onye isi ụlọ ọrụ na-edu ndú; PhD natara na Fudan University na organic onwu. Ihe karịrị afọ itoolu nke ahụmịhe na njikọ njikọ nke kemịkal ọgwụ. Ahụmịhe bara ụba na kemịlị jikọtara ọnụ, kemịkal ọgwụ na njikọta omenaala na njikwa ọrụ.

References

1. Stasi, MA, Scioli, MG, Arcuri, G., Mattera, GG, Lombardo, K., Marcellini, M.,… & Borsini, F. (2010). Propionyl-l-carnitine na-eme ka mgbake ọbara gbasaa na arteriogenesis revascularization ma na-ebelata endothelial NADPH-oxidase 4-mediated superoxide production. Arteriosclerosis, thrombosis, na usoro akwara ọmụmụ, 30(3), 426-435.
2. Gianfrilli, D., Lauretta, R., Di Dato, C., Graziadio, C., Pozza, C., De Larichaudy, J.,… & Lenzi, A. (2012). Propionyl ‐ l ‐ carnitine, l ‐ arginine na niacin na ọgwụ mmekorita nwoke na nwanyi: usoro nri nke na-edozi aru. Andrologia, 44, 600-604.
3. Flayyih, NK (2015). Nsonaazụ nke L-carnitine nyere ụmụ oke dị ime na omumu ihe omumu nke ụmụ nwanyị. Akwụkwọ akụkọ Wassit For Science & Medicine, 8(1), 97-104.

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