Glycine Propionyl-L-Carnitine (GPLC): Mgbakwunye Kachasị mma Maka Nrụpụta Ahụ

Gịnị Bụ Glycine Propionyl-L-Carnitine (GPLC)

Glycine Propionyl-L-Carnitine na-ekwu okwu na-ezo aka n'ụdị njikọ njikọta nke propionyl-L-carnitine na amino acid glycine. Ekesa ya na ezi n’ulo dika Carnitine ma dikwa nkiti na nmebe Creine. Glycine Propionyl-L-Carnitine (GPLC) na-arụ ọrụ dị ka antioxidant, ọ na-ebutekwa ọgụ dị egwu megide nnwere onwe nnwere onwe yana ichebe na peroxidation lipid.

Ọzọkwa, ọ na-enyere aka n'ịmepụta ume site na-enyere aka na-ebufe fatty acids na-ebu ogologo n'ime mitochondria. Ọ na - enyere aka n'iwepụ ihe mkpofu - enyemaka carnitine na nchekwa nke ahụ site na ọrịa obi na ọrịa shuga. A na-ewere GPLC ka ọ nwee ọrụ nke na-akpali akpali ahụ ike ma na-eme ka mmega ahụ dịkwuo elu. Enwere ike iwere mgbakwunye ahụ yana mgbakwunye ndị ọzọ, dịka ọmụmaatụ, propionyl-l-carnitine l-arginine na niacin, nke na-enyere aka iji melite nrụrụ erectile (ED) n'ime ụmụ nwoke. Otú ọ dị, nweta ọgwụ ziri ezi site na dọkịta gị iji zere ị overụbiga mmanya ókè, nke nwere ike ịkpata nnukwu mmetụta dị egwu.

Propionyl-l-carnitine ụdị gụnyere; 3-propanoyloxy-4- (trimethylazaniumyl) butanoate, Glycine Propionyl-L-Carnitine (423152-20-9), L-carnitine propionyl, PLC, LPC, na Glycine propionyl-L-Carnitine Hydrochloride. Na Mgbakwunye nri na-ere n'okpuru aha ika dị iche iche dabere na ọnọdụ gị. Agbanyeghị, nke ahụ ekwesịghị ịbụrụ gị nsogbu; mediki ga enwe ike iduzi n’zuta ya.

Mgbakwunye a dị na ụlọ ahịa dị n'ịntanetị dị iche iche ebe ị nwekwara ike ibubata ya n'enweghị nsogbu. Dịka ọmụmaatụ, propionyl-l-carnitine Walmart na-anapụta n'ime obere oge enwere ike. Ọ baghị uru ebe ị nọ, jiri ekwentị gị ma ọ bụ kọmpụta gị mee iwu Walmart propionyl-l-carnitine. Ọ bụ ihe amamihe dị na ịme nyocha gị maka ndị na-ere glycine propionyl dịnụ tupu ịme mkpebi ikpeazụ gị. Gụọ nyocha propionyl-l-carnitine Reddit iji nweta nkọwa nke otu ndị na-ere ma ọ bụ mgbakwunye na-arụ ọrụ. Ndị ahịa na-ekwupụta n'eziokwu n'eziokwu ha gbasara mgbakwunye, nke nwere ike inyere gị aka ịhọrọ onye na-ere ahịa kacha mma. Dọkịta gị ga-abụkwa onye kachasị mma iduzi gị ebe na otu esi enweta mgbakwunye dị mma nke ga - enyere gị aka iru ihe mgbaru ọsọ gị.

 

Glycine Propionyl-L-Carnitine na L-Carnitine

A maara GPCL dị ka Carnitine's propionyl ester nke nwere ihe ọzọ nke glycine. N'ihi anụ ahụ nke enzymes esterase, Glycine Propionyl-L-Carnitine testosterone kwesịrị ịrụ ọrụ nke prodrug ma rụpụta glycine, Carnitine, yana propionic acid dị na ahụ mmadụ. Glycine Propionyl-L-Carnitine na L-Carnitine dị iche na otu akụkụ. Ha abuo na enyere aka na imeputa ike yana ahụ ike. Glycine propionyl-L-carnitine na-enyocha na-enyere ahụ gị aka ịgbake n'ọrịa ndị dị ka ọrịa obi.

Kama nke ahụ, a na-ejikarị L-Carnitine eme ihe n'ịgwọ mgbu nke ụkwụ yana ọrịa obi. L-Carnitine bụ kemịkalụ ebe Glycine Propionyl-L-Carnitine (423152-20-9) na-enyocha bụ molekụla. Na nkenke, testosterone Glycine Propionyl-L-Carnitine na-alụ ọgụ ka ọrịa L-Carnitine na-agwọ ọrịa.

 

Mmetụta Glycine Propionyl-L-Carnitine

Ndị na-esonụ bụ Nke a bụ glycine propionyl L uru carnitine:

• Inye ike. Propionyl-L-carnitine na-enyere ahụ aka imepụta ike. Ọ dị mkpa maka ịrụ ọrụ obi kwesịrị ekwesị, mmegharị nke akwara, n'etiti usoro ahụ ndị ọzọ. Ọ bụkwa ya na-eme ka ọbara na-ekesa n’ime ahụ.

• Na-emeso ọkwa testosterone dị ala. Ka nká nwere ike ime ka mmadụ nwee testosterone dị ala. Propionyl-L-carnitine tinyere acetyl-L-carnitine ruo ọnwa isii bụ ọgwụgwọ maka ala arụ ọrụ mmekọahụ, obi nkoropụ na ike ọgwụgwụ nke ụmụ nwoke. Nchikota a na aru oru dika testosterone synthetic.

• Angina ma ọ bụ obi mgbu. Iburu propionyl-L-carnitine site na ọnụ na-enyere ndị nwere angina ije ije ihu. Somefọdụ ndị mmadụ, o nwere ike belata ugboro ole nke mgbu obi.

 

 

• Ọ na-agwọ ọrịa obi mgbu na-adịghị ala ala. Mgbe ị banye na ọgwụ propionyl-L-carnitine na akwara, ọ na - enyere aka ịmịpụta mkpụrụ obi ka ọ dị mma n'ebe ndị mmadụ nwere ọrịa obi.

• Congestive obi nkụchi (CHF). Propionyl-L-carnitine bụ prodrug nke na-arụ ọrụ maka ndị nwere oke CHF na-agbanwe agbanwe. Ọ na - eme ka obi ha na - arụ ọrụ ma nyere ha aka ije ije ogologo ije.

• Glycine propionyl l carnitine na dysfunction erectile. Site na ịba ụba homonụ nke testosterone n’ime ahụ gị, mgbakwunye a na-edozi nsogbu nsogbu etrectile na-abawanye na ịbawanye na nwoke na nwoke.

• A na-agwakọta Propionyl-L-carnitine na Viagra (sildenafil) maka nsonaazụ kachasị mma na ụmụ nwoke nwere ED na ọrịa shuga. Ọzọkwa, ihe ndị akọwapụtara nwere protein propionyl-L-carnitine nwere ike ịkwalite arụmọrụ mmekọahụ.

• Ọrịa vaskụla nke Peripheral. Ọrịa Peripheral nwere ike ibute ọria veins ma ọ bụ ihe mgbu n'ụkwụ mgbe ị na-eje ije; ọnọdụ a na-akpọ ịkọwa ọnụ. Ọgwụ agịga ma ọ bụ ịmalite Propionyl-L-carnitine na-enyere ndị mmadụ aka na-enwe ihe mgbu ụkwụ ije ogologo ije.

• Ọrịa Peyronie (ọ na-eme ka anụ ahụ amụ)Otu ọgwụ a na-akpọ verapamil, yana propionyl-L-carnitine na-eme ka mmekọahụ nwee mmekọahụ, na-egbochi njọ nke ọnọdụ ahụ. Enwere ike iji mkpokọta ọnụ ma ọ bụ site na injections. Ọrịa Peyronie nwere ike ịchọ ịwa ahụ ma ọ bụrụ na ọ nweghị ya. N'ihi ya, Propionyl-L-Carnitine na-abịa napụta.

• Ọrịa afọ (ọnya afọ). Propionyl-L-carnitine bara uru iji belata ihe mgbaàmà na ndị ọrịa nwere ọnya afọ na-ejikwa ọgwụ ụfọdụ. Ọ nwere ike iwepụ ihe mgbaàmà ahụ.

 

 Nnyocha na Nsonaazụ Glycine Propionyl-L-Carnitine

• Ọrịa Crohn (ọrịa afọ)Nchoputa nke mbu gosiputara na iji propionyl-L-carnitine bu ihe na-ebelata ihe mgbaàmà nke ndi oria na oria Crohn.

• Ala ala ike ọgwụgwụ (CFS).Nnyocha na-atụ aro na propionyl-L-carnitine nwere ike melite ike ọgwụgwụ n'ozuzu maka ndị ọrịa CFS. N'ụzọ na-akpali mmasị, ọ bụrụ na agwakọta acetyl-L-carnitine na propionyl-L-carnitine, nsonaazụ ahụ adịghị arụ ọrụ karịa iji otu emeju ọzọ.

• Ike mmega ahụ. E gwuru ga-eme ka mmerụ ahụ dịkwuo elu, ike ịkwụsi ike mmega ahụ siri ike. Agbanyeghị, were nke ọma glycine propionyl-l-carnitine usoro onunu ogwu. Doagbaso mmezi a nwere ike ibute nsonaazụ HCl mmetụta nke glycine propionyl-l-carnitine, nke nwere ike ịdị ọnụ iji gbanwee.

 

Olee nri ndị bara ụba na Glycine Propionyl-L-Carnitine?

Glycine propionyl-l-carnitine ka ahutara na:

• Ala ahịhịa juru.
• beef
• Anụ ezi
• Chicken chiiz
• mkpụrụ

Etu ị ga-ewere Glycine Propionyl-L-Carnitine

A na-ere Propionyl-L-Carnitine dị ka mgbakwunye. Nwere ike ịchọta ya na ụlọ ahịa mpaghara gị ma ọ bụ ụlọ ahịa ọgwụ. Ndị na-eme egwuregwu nwere ike irite uru dị ukwuu site na ị itụ ya ebe ọ bụ na ọ na-enyere ahụ aka ịnọgide na-enwe ọrụ akwara dị mma ma na-eme ka ikike ikpo ọkụ nke mkpụrụ ndụ dịkwuo ike. Lee ndị a tụrụ aro Glycine Propionyl-L-Carnitine (423152-20-9) usoro onunu ogwu akwadoro site na nyocha sayensị.

 EGO:

• Iji gwọọ nsogbu arịa ọbara: Were 500-2000 mg propionyl-L-carnitine ugboro abụọ n'ụbọchị.
• Iji dozie CHF (ọrịa obi ụkọ), angina ma ọ bụ obi mgbu; Were 500 mg propionyl-L-carnitine ugboro atọ n'ụbọchị.
• Iji bulie testosterone na ụmụ nwoke mere agadi: Were gram abụọ nke propionyl-L-carnitine na gram abụọ nke acetyl-L-carnitine kwa ụbọchị.
• Glycine propionyl l carnitine na dysfunction erectile: Were gram 2 nke propionyl-L-carnitine kwa ụbọchị na 50 mg nke nyere ugboro abụọ kwa izu. Nchikota nkwekorita nke propionyl-L-carnitine l-arginine na niacin ga - ewulite mmeko nwoke na nwanyi. Agbanyeghị, usoro onunu ogwu kwesiri ibu 250mg fir propionyl-L-carnitine na 20mg maka niacin. N'aka nke ozo, ị nwekwara ike were mgbakwunye na arginine 2500 mg kwa ụbọchị.
• Maka ọrịa Peyronie: gram 2 nke propionyl-L-carnitine kwa ụbọchị yana injections nke ọgwụ a na-akpọ verapamil.
• Maka ọnya afọ: 0.5-1 gram nke propionyl-L-carnitine ugboro abụọ kwa ụbọchị.

I nwekwara ike ijikọ l -carnitine, na Cialis, mana nweta usoro ọgwụgwọ kwesịrị ekwesị site n'aka ndị ọkachamara ahụike maka ahụmịhe kachasị mma.

NSOGBU:

Maka ọrịa obi na nsogbu arịa ọbara: Ọkachamara ahụike na-eduzi inyonya propionyl-L-carnitine, usoro ana - akpọ IV.

 

Glycine Propionyl-L-Carnitine mmetụta na nchekwa

Propionyl-L-carnitine bụ ihe dị mma maka ọtụtụ mmadụ mgbe ọnụ ma ọ bụ tinye ya n ’akwara site n’aka dọkịta ọkachamara. Ọ nwere ike ibute afọ ọsịsa, afọ mgbu, afọ mgbu, vomiting, azụ mgbu, na obi ọrịa. Ọzọkwa, ọ nwere ike ibute iku ume, mmamịrị, ma ọ bụ ọsụsọ.

 

 

ịkpachara anya

Ndị ọrụ afọ ime na ndị na-enye nwa ara: A maghị ihe dị ukwuu maka ojiji nke propionyl-L-carnitine maka ịctụ nwa. Jiri nwayọ gaa n’ihu ma zere iji ya.

"Underactive thyroid" (hypothyroidism): propionyl-L-carnitine nwere ike ime ka hypothyroidism ka njọ ma ọ bụ ọgwụgwọ ọgwụgwọ thyroid adịghị arụ ọrụ. Chemical dị na ọgwụ ahụ, ya bụ, L-carnitine, na-egbochi hormone thyroid. Ọ kachasị mma iji zere propionyl-L-carnitine ma ọ bụrụ na ị nwere hypothyroidism.

Ọ ọdịdọ: mmadụ ole na ole nwere akụkọ ihe ọdịnala na-ekwu na mmụba nke ogo yana ọnya ọnya mgbe ha jisịrị L-carnitine. Enwere ohere dị ukwuu na nke a nwere ike ime na propionyl-L-carnitine ebe ọ nwere kemịkal yiri ya.

 

Mmekorita nke GPLC na ogwu ndi ozo

• Iji nọrọ n'akụkụ nchebe, gakwuru dọkịta gị tupu ịmalite na-ewere GPLC. Bụrụ na ị na-ewere Acenocoumarol (Sintrom), ị ga-etinyekwa dọkịta gị maka na ọ nwere ike inwe mkparịta ụka dị nro n'ihi na ọ nwere ike belata ịmịnye ọbara ebe GPLC nwere ike ịbawanye mmetụta Sintrom.

• Warfarin (Coumadin) bụ ọgwụ ọzọ ị nwere ike ịnakọta yana mgbakwunye glycine propionyl-l-carnitine. Otú ọ dị, jide n'aka na ị ga-enweta ezigbo usoro ọgwụgwọ site na ọgwụ gị. Usoro onunu ogwu nwere ike ịdị iche dabere na ọnọdụ dị n'okpuru ọgwụgwọ.

 

Ebe ị ga-azụta mgbakwunye Propionyl-L-Carnitine

Dịka ngwaahịa ọgwụ ọ bụla ọzọ, ị nwere ike ịzụta mgbakwunye glycine Propionyl-L-Carnitine sitere na nyiwe dị iche iche dị n'ịntanetị ma ọ bụ ọbụna na ụlọ ọgwụ ahụ ike. Agbanyeghị, ihe ịma aka na-abịa n'ịhọrọ ndị na-ere ahịa kwesịrị ekwesị nke ga-enye gị ngwaahịa dị mma. Enwere ọtụtụ ndị na-ere glycine Propionyl-l-Carnitine, ma nke anụ ahụ ma n'ịntanetị. Otú ọ dị, nke ahụ ekwesịghị ịtụ gị ụjọ, ihe ịchọrọ bụ iwepụta oge gị ma mee nyocha banyere ndị na-ere ahịa glycine Propionyl-l-Carnitine dị.

I nwere nnwere onwe ịzụta glycine Propionyl l-Carnitine nnukwu ntụ ntụ ma ọ bụ naanị ezuru gị iji. Cheta, iji nweta usoro ọgwụgwọ ziri ezi mgbe niile site n'aka onye ọrụ ahụike ka ị nwee ike ịnụ ụtọ glycine propionyl-L-carnitine kachasị. Tụlee ịgafe propionyl-l-carnitine Redditreviews iji nweta nnyocha nke ahụmịhe onye ọrụ dị iche iche. I nwekwara ike ịzụta l carnitine na Cialis site n'aka otu ndị na-ere ahịa, n'etiti mgbakwunye ndị ọzọ. Brandsdị Propionyl-l-carnitine dịgasị iche site n'otu ebe gaa na nke ọzọ, mana ọ ka bụ otu mgbakwunye ahụ. Kwenye dọkịta gị tupu ị nye iwu ahụ.

 

References

1. Stasi, MA, Scioli, MG, Arcuri, G., Mattera, GG, Lombardo, K., Marcellini, M.,… & Borsini, F. (2010). Propionyl-l-carnitine na-eme ka mgbake ọbara gbasaa na arteriogenesis revascularization ma na-ebelata endothelial NADPH-oxidase 4-mediated superoxide production. Arteriosclerosis, thrombosis, na usoro akwara ọmụmụ, 30(3), 426-435.
2. Gianfrilli, D., Lauretta, R., Di Dato, C., Graziadio, C., Pozza, C., De Larichaudy, J.,… & Lenzi, A. (2012). Propionyl ‐ l ‐ carnitine, l ‐ arginine na niacin na ọgwụ mmekorita nwoke na nwanyi: usoro nri nke na-edozi aru. Andrologia, 44, 600-604.
3. Flayyih, NK (2015). Nsonaazụ nke L-carnitine nyere ụmụ oke dị ime na omumu ihe omumu nke ụmụ nwanyị. Akwụkwọ akụkọ Wassit For Science & Medicine, 8(1), 97-104.

Comments